STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
best-24Bestrophin homolog 24; Forms chloride channels. (632 aa)    
Predicted Functional Partners:
kvs-4
Probable voltage-gated potassium channel subunit kvs-4; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes.
      
 0.758
twk-47
Ion_trans_2 domain-containing protein.
      
 0.740
clh-5
Chloride channel protein.
      
 0.700
acd-5
Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
  
 0.699
clh-6
Chloride channel protein.
      
 0.692
lgc-53
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.692
kcnl-2
CaMBD domain-containing protein.
   
  
 0.676
gab-1
Gamma-aminobutyric acid receptor subunit beta; GABA, an inhibitory neurotransmitter, mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily.
   
  
 0.671
che-6
Cyclic nucleotide-binding domain-containing protein.
      
 0.663
clh-1
Chloride channel protein.
   
  
 0.617
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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