STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
baz-2Bromodomain Adjacent to Zinc finger domain, 2A/2B, homolog. (1390 aa)    
Predicted Functional Partners:
isw-1
Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
   
 
 0.861
T26A5.8
CBFD_NFYB_HMF domain-containing protein.
    
 
 0.765
ver-4
Tyrosine-protein kinase receptor ver-4; Receptor tyrosine kinase which may be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail.
    
 
 0.709
ver-1
Protein ver-1; Involved in amphid glia remodeling during entry into dauer stage by promoting the fusion of sheath amphid cells which encloses AWC neuron sensory endings. May be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail.
    
 
 0.708
ver-3
Tyrosine-protein kinase receptor ver-3; Receptor tyrosine kinase which may be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail.
   
 
 0.677
K09C6.8
Uncharacterized protein.
      
 0.660
lig-1
DNA ligase 1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
  
 0.654
pct-1
Cyclin-dependent kinase 17; Serine/threonine-protein kinase, which, in association with cyy-1, regulates the trafficking of synaptic vesicles in the DA9 motor neuron and probably also in the DD motor neurons and in RIA interneurons.
   
  
 0.557
Y50D4A.1
Uncharacterized protein.
   
 
 0.463
cec-1
Chromo domain-containing protein cec-1.
   
 
 0.457
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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