STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hdl-1Probable aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine; Belongs to the group II decarboxylase family. (905 aa)    
Predicted Functional Partners:
tph-1
BH4_AAA_HYDROXYL_2 domain-containing protein.
   
 0.867
alh-4
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.808
alh-5
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.808
alh-10
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
   
 0.806
alh-7
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
   
 0.806
alh-12
Aldedh domain-containing protein.
   
 0.806
alh-11
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
   
 0.805
alh-1
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
   
 0.805
alh-2
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
   
 0.805
alh-6
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.803
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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