node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F35G12.11 | rnp-1 | F35G12.11.2 | ZK863.7a.1 | Enhancer of rudimentary homolog; May have a role in the cell cycle. | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | 0.510 |
F35G12.11 | rnp-2 | F35G12.11.2 | K08D10.4.1 | Enhancer of rudimentary homolog; May have a role in the cell cycle. | RNP (RRM RNA binding domain) containing. | 0.575 |
F35G12.11 | uaf-1 | F35G12.11.2 | Y92C3B.2a.1 | Enhancer of rudimentary homolog; May have a role in the cell cycle. | Splicing factor U2AF 65 kDa subunit; Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns early during spliceosome assembly (By similarity). | 0.447 |
cdc-25.3 | oma-2 | ZK637.11.1 | ZC513.6.1 | M-phase inducer phosphatase cdc-25.3. | CCCH-type zinc finger protein oma-2; Zinc-finger RNA-binding protein that binds to 5'-UA[AU]-3' motifs in the 3'-UTR of maternal mRNAs to suppress translation in oocytes and embryos. Acts redundantly with oma-1 to control the temporal expression and distribution of maternal proteins and thereby promote meiotic progression, oocyte maturation, fertilization and embryonic development. Also, together with oma-1, is involved in P-granule distribution during embryonic development. | 0.796 |
cdc-25.3 | rnp-1 | ZK637.11.1 | ZK863.7a.1 | M-phase inducer phosphatase cdc-25.3. | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | 0.713 |
cdc-25.3 | spn-4 | ZK637.11.1 | ZC404.8.2 | M-phase inducer phosphatase cdc-25.3. | RRM domain-containing protein. | 0.733 |
cdc-25.3 | zif-1 | ZK637.11.1 | F59B2.6.1 | M-phase inducer phosphatase cdc-25.3. | Zinc finger-interacting factor 1; Probable substrate recognition component of a CBC (Cul2- ElonginB-ElonginC) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Ensures germline precursor cell asymmetry by targeting germline proteins for destruction if expressed in non-germline cells. This process also requires elc-1, cul-2, rbx-1 and ubc-2. | 0.701 |
eif-2A | rnp-1 | E04D5.1a.2 | ZK863.7a.1 | Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner; Belongs to the WD repeat EIF2A family. | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | 0.526 |
oma-2 | cdc-25.3 | ZC513.6.1 | ZK637.11.1 | CCCH-type zinc finger protein oma-2; Zinc-finger RNA-binding protein that binds to 5'-UA[AU]-3' motifs in the 3'-UTR of maternal mRNAs to suppress translation in oocytes and embryos. Acts redundantly with oma-1 to control the temporal expression and distribution of maternal proteins and thereby promote meiotic progression, oocyte maturation, fertilization and embryonic development. Also, together with oma-1, is involved in P-granule distribution during embryonic development. | M-phase inducer phosphatase cdc-25.3. | 0.796 |
oma-2 | rnp-1 | ZC513.6.1 | ZK863.7a.1 | CCCH-type zinc finger protein oma-2; Zinc-finger RNA-binding protein that binds to 5'-UA[AU]-3' motifs in the 3'-UTR of maternal mRNAs to suppress translation in oocytes and embryos. Acts redundantly with oma-1 to control the temporal expression and distribution of maternal proteins and thereby promote meiotic progression, oocyte maturation, fertilization and embryonic development. Also, together with oma-1, is involved in P-granule distribution during embryonic development. | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | 0.509 |
oma-2 | spn-4 | ZC513.6.1 | ZC404.8.2 | CCCH-type zinc finger protein oma-2; Zinc-finger RNA-binding protein that binds to 5'-UA[AU]-3' motifs in the 3'-UTR of maternal mRNAs to suppress translation in oocytes and embryos. Acts redundantly with oma-1 to control the temporal expression and distribution of maternal proteins and thereby promote meiotic progression, oocyte maturation, fertilization and embryonic development. Also, together with oma-1, is involved in P-granule distribution during embryonic development. | RRM domain-containing protein. | 0.901 |
oma-2 | zif-1 | ZC513.6.1 | F59B2.6.1 | CCCH-type zinc finger protein oma-2; Zinc-finger RNA-binding protein that binds to 5'-UA[AU]-3' motifs in the 3'-UTR of maternal mRNAs to suppress translation in oocytes and embryos. Acts redundantly with oma-1 to control the temporal expression and distribution of maternal proteins and thereby promote meiotic progression, oocyte maturation, fertilization and embryonic development. Also, together with oma-1, is involved in P-granule distribution during embryonic development. | Zinc finger-interacting factor 1; Probable substrate recognition component of a CBC (Cul2- ElonginB-ElonginC) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Ensures germline precursor cell asymmetry by targeting germline proteins for destruction if expressed in non-germline cells. This process also requires elc-1, cul-2, rbx-1 and ubc-2. | 0.809 |
pir-1 | rnp-1 | T23G7.5a.1 | ZK863.7a.1 | RNA/RNP complex-1-interacting phosphatase homolog; Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity (By similarity). Binds RNA (By similarity). During small-RNA-mediated gene- silencing or RNA interference (RNAi), involved in the dcr-1-mediated processing of an amplified dsRNA intermediate. | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | 0.577 |
rnp-1 | F35G12.11 | ZK863.7a.1 | F35G12.11.2 | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | Enhancer of rudimentary homolog; May have a role in the cell cycle. | 0.510 |
rnp-1 | cdc-25.3 | ZK863.7a.1 | ZK637.11.1 | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | M-phase inducer phosphatase cdc-25.3. | 0.713 |
rnp-1 | eif-2A | ZK863.7a.1 | E04D5.1a.2 | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner; Belongs to the WD repeat EIF2A family. | 0.526 |
rnp-1 | oma-2 | ZK863.7a.1 | ZC513.6.1 | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | CCCH-type zinc finger protein oma-2; Zinc-finger RNA-binding protein that binds to 5'-UA[AU]-3' motifs in the 3'-UTR of maternal mRNAs to suppress translation in oocytes and embryos. Acts redundantly with oma-1 to control the temporal expression and distribution of maternal proteins and thereby promote meiotic progression, oocyte maturation, fertilization and embryonic development. Also, together with oma-1, is involved in P-granule distribution during embryonic development. | 0.509 |
rnp-1 | pir-1 | ZK863.7a.1 | T23G7.5a.1 | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | RNA/RNP complex-1-interacting phosphatase homolog; Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity (By similarity). Binds RNA (By similarity). During small-RNA-mediated gene- silencing or RNA interference (RNAi), involved in the dcr-1-mediated processing of an amplified dsRNA intermediate. | 0.577 |
rnp-1 | rnp-2 | ZK863.7a.1 | K08D10.4.1 | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | RNP (RRM RNA binding domain) containing. | 0.987 |
rnp-1 | spn-4 | ZK863.7a.1 | ZC404.8.2 | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. | RRM domain-containing protein. | 0.520 |