STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pxn-1Peroxidasin homolog; Belongs to the peroxidase family. XPO subfamily. (1285 aa)    
Predicted Functional Partners:
act-5
ACTin.
   
 
 0.918
pxn-2
PeroXidasiN (Drosophila peroxidase) homolog.
  
 
0.819
gpd-1
Glyceraldehyde-3-phosphate dehydrogenase 1.
    
 
 0.770
gpx-2
Glutathione peroxidase 2; May constitute a glutathione peroxidase-like protective system against oxidative stresses.
   
 
 0.769
gpd-4
Glyceraldehyde-3-phosphate dehydrogenase 4.
    
 
 0.767
gpd-3
Glyceraldehyde-3-phosphate dehydrogenase 3.
   
 
 0.752
gpd-2
Glyceraldehyde-3-phosphate dehydrogenase 2.
   
 
 0.748
lat-1
Latrophilin-like protein 1; Has a role in the establishment of anterior-posterior polarity in tissues during embryogenesis. Required for the alignment of the mitotic spindles and division planes. May have a role in cell death events. Required for normal defection and oocyte fertilization. Involved in sperm function. Operates in pharyngeal pumping during feeding. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    
 
 0.723
gpx-4
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.712
gpx-5
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.709
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.