| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SLG_29720 | SLG_29750 | SLG_29720 | SLG_29750 | Hypothetical protein. | Hypothetical protein. | 0.419 |
| SLG_29720 | glyA | SLG_29720 | SLG_29740 | Hypothetical protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.440 |
| SLG_29720 | nrdR | SLG_29720 | SLG_29760 | Hypothetical protein. | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.425 |
| SLG_29720 | rpiB | SLG_29720 | SLG_29730 | Hypothetical protein. | Ribose 5-phosphate isomerase B. | 0.485 |
| SLG_29750 | SLG_29720 | SLG_29750 | SLG_29720 | Hypothetical protein. | Hypothetical protein. | 0.419 |
| SLG_29750 | glyA | SLG_29750 | SLG_29740 | Hypothetical protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.781 |
| SLG_29750 | nrdR | SLG_29750 | SLG_29760 | Hypothetical protein. | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.810 |
| SLG_29750 | rpiB | SLG_29750 | SLG_29730 | Hypothetical protein. | Ribose 5-phosphate isomerase B. | 0.717 |
| glyA | SLG_29720 | SLG_29740 | SLG_29720 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hypothetical protein. | 0.440 |
| glyA | SLG_29750 | SLG_29740 | SLG_29750 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hypothetical protein. | 0.781 |
| glyA | nrdR | SLG_29740 | SLG_29760 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.852 |
| glyA | rpiB | SLG_29740 | SLG_29730 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Ribose 5-phosphate isomerase B. | 0.985 |
| nrdR | SLG_29720 | SLG_29760 | SLG_29720 | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Hypothetical protein. | 0.425 |
| nrdR | SLG_29750 | SLG_29760 | SLG_29750 | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Hypothetical protein. | 0.810 |
| nrdR | glyA | SLG_29760 | SLG_29740 | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.852 |
| nrdR | rpiB | SLG_29760 | SLG_29730 | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Ribose 5-phosphate isomerase B. | 0.790 |
| rpiB | SLG_29720 | SLG_29730 | SLG_29720 | Ribose 5-phosphate isomerase B. | Hypothetical protein. | 0.485 |
| rpiB | SLG_29750 | SLG_29730 | SLG_29750 | Ribose 5-phosphate isomerase B. | Hypothetical protein. | 0.717 |
| rpiB | glyA | SLG_29730 | SLG_29740 | Ribose 5-phosphate isomerase B. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.985 |
| rpiB | nrdR | SLG_29730 | SLG_29760 | Ribose 5-phosphate isomerase B. | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.790 |