STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
atm1Probable composite transport ATP-binding permease protein. Homology to amt1 of S. cereviciae of 48% (sprot|ATM1_YEAST). COULD BE INVOLVED IN THE TRANSPORT OF yet unknow substrates (probable HEME) FROM THE MITOCHONDRIA TO THE CYTOSOL. InterPro: ABC transporter transmembrane region (IPR001140), ATP/GTP-binding site motif A (P loop) (IPR001687), ABC transporter (IPR003439),AAA_ATPase sperfamily (IPR003593) Pfam: ATP transporter,ABC transporter transmembrane region no signal peptide probable 6 TMHs; Specificity unclear. (603 aa)    
Predicted Functional Partners:
prfA
Peptide chain release factor; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
  
  0.745
azo3632
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q89UA9 (44% identity); TREMBL:Q92M72 (44% identity); SWISSPROT:Q9JI39 (32% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site mo [...]
  
 
0.735
msbA1
Lipid A export ATP-binding/permease protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
  
 
0.731
azo0454
Conserved hypothetical threonine efflux protein. Homology to rsc0148 of R. solanaxearum of 52% (trembl|Q8Y2B8). InterPro: Lysine exporter protein (LYSE/YGGA) (IPR001123) Pfam: LysE type translocator Tigrfam: 2A76: Homoserine/Threonine efflux protein signal peptide Probable 6 TMHs; Family membership.
       0.709
azo2312
Conserved hypothetical membrane protein. Homology to Avin02002177 of Azotobacter vinelandii of 61% (gi|53611929|ref|ZP_00090985.2|(NBCI ENTREZ)). InterPro: ABC transporter (IPR003439). Pfam: ABC transporter. no signal peptide. 5 TMHs; Conserved hypothetical protein.
    
 0.701
azo0660
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q87G83 (52% identity); TREMBL:Q9K1A3 (61% identity); SWISSPROT:Q57180 (60% identity). Pfam (PF00005): ABC transporter. TMHMM reporting five transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC [...]
    
 0.696
azo1236
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q88H94 (52% identity); TREMBL:Q9RXZ1 (29% identity); SWISSPROT:Q9WYC4 (25% identity). Pfam (PF00664): ABC transporter transmembrane region. Pfam (PF00005): ABC transporter. TMHMM reporting six transmembra [...]
    
 0.696
azo2785
Conserved hypothetical membrane protein. Homology to SC3D11.05C of Streptomyces coelicolor of 33% (trembl|Q9L1F7(SRS)). Pfam (PF00005): ABC transporter. Pfam (PF00664): ABC transporter transmembrane region. TMHMM reporting three transmembrane helices. No signal peptide; Conserved hypothetical protein.
    
 0.696
msbA2
Lipid A export ATP-binding/permease protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
    
 0.696
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
 
 0.605
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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