STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
treZMalto-oligosyltrehalose trehalohydrolase(MTHase) (4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase) (Maltooligosyl trehalose trehalohydrolase).Involved in the trehalose biosynthesis,hydrolysing alpha-(1->4)-d-glucosidic linkage in 4-alpha-d-{(1->4)-alpha-d-glucanosyl}(n) trehalose to yield trehalose and alpha-(1->4)-d-glucan. 42% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.PF02922; isoamylase_N; 1; Specificity unclear. (686 aa)    
Predicted Functional Partners:
azo1799
The first part of the protein (2202 bases) is 37% Glyco_hydro_77. Pfam:PF02446; 4A_glucanotrans; 1.TIGRFAMs:TIGR00217; malQ; 1. GO:5975/4134. The second part of the protein (from the base 2128 to the end) is 39%; Function unclear; ORF5.
 
 0.998
glgC
Putative glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.982
glgX
Putative glycogen debranching enzyme; Glycogen operon protein GlgX homolog.Hydrolyzes the alpha-1,6-glucosidic linkages in glycogen which has first been partially depolymerized by phosphorylase. Shows only very little activity with native glycogen. 46% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.F02922; isoamylase_N; 1; High confidence in function and specificity; Belongs to the glycosyl hydrolase 13 family.
 
0.964
treS
Trehalose synthase(Maltose alpha-D-glucosyltransferase).Catalyzes the conversion of maltose into alpha,alpha- trehalose by transglucosylation. 54% Alp_amyl_cat_sub.IPR006047; Alpha_amyl_cat.InterPro: Glycoside hydrolase family 13. Pfam:PF00128; alpha-amylase; 1; High confidence in function and specificity.
 
 
0.949
pep1
Putative glucanohydrolase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
 
 
 0.925
glgA
Putative glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
 
 
 0.923
glgB2
14-alpha-glucan branching enzyme (Glycogen branching enzyme)(BE) (14-alpha-D-glucan:14-alpha-D-glucan 6-glucosyl- transferase). Catalyzes the formation of the alpha-16-glucosidic linkages in glycogen by scission of a 14-alpha-linked oligosaccharide from growing alpha-14-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-16 position. 36% Alpha_amyl_cat.IPR006407;GlgB.IPR004193;Glyco_hydro_13N. Pfam:PF00128; Alpha-amylase; 1.PF02922; Isoamylase_N; 1. TIGRFAMs:TIGR01515; branching_enzym; 1; High confidence in function and specificity.
 
 
 
0.826
azo1791
Conserved hypothetical secreted protein. Homology to ebA6930 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA6930(KEGG)). No domains predicted. Signal peptide present. No TMH reported present; Conserved hypothetical protein.
 
    0.799
azo1795
Conserved hypothetical protein; DNA topoisomerase I (EC 5.99.1.2). The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. cbiB: cobalamin biosynthesis protein; Specificity unclear.
 
    0.756
palZ
Putative alpha-D-1,4-glucosidase; Alpha -D-1,4-glucosidase, PalZ. Involved in the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. 55% Alpha_amyl_cat.IPR006589; Alp_amyl_cat_sub.IPR006046; Glyco_hydro_13. Pfam:PF00128; Alpha-amylase;1; High confidence in function and specificity.
 
 
0.744
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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