STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
azo2263Putative amino acid-binding protein. Homology to fliy of E. coli of 26% (AAC43545). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR amino acids. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR1638); solute binding protein/glutamte receptor (IPR001311) Pfam: Bacterial extracellular solute-binding protein signal peptide no TMHS hisG: ATP phosphoribosyltransferase; Specificity unclear. (272 aa)    
Predicted Functional Partners:
azo2265
Conserved hypothetical amino acid permease. Homology to pspto5247 of P. syringae (trembl|Q87UP9). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE (BY SIMILARITY). Interpro: binding-protein-depenent transport system inner membrane component (IPR000515). Pfam: Binding-protein-dependent transport system. no signal peptide. 3 TMHs; Specificity unclear.
 0.997
azo2264
Amino acid ABC transporter, permease protein, 75% Identity to TrEMBL;Q87UQ0, 65% Identity to TrEMBL;Q8XXK9,Q6F6T8. Has PF00528; IPR000515, BPD_transp; Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system. The integral inner-membrane proteins translocate the substrate across the membrane. It has been shown that most of these p [...]
 
 0.996
glnQ2
Probable glutamine transport ATP-binding protein. Homology with glnQ of B. stearothermophilus of 53% (sprot|GLNQ_BACST). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR GLUTAMINE. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. InterPro: AAA ATPase superfamily (IPR003593), ABC_Transporter (IPR003439), ATP/GTP_binding site motif A (P-loop) (IPR001687) Pfam: ABC transporter no signal peptide no TMHs mobB: molybdopterin-guanine dinucleotid; High confidence in function and specificity.
 
 0.996
glnM
Putative glutamine transport permease protein. Homology to glnM of B. subtilis of 30% (TREMBL:O34671) Probably part of the binding-protein-dependent transport system of amino acids. Probably responsible for the translocation of the substrate across the membrane InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein-dependent transport systems inner membrane component no signal peptide probable 5 TMHs; Family membership.
 0.918
aapQ
Putative amino acid permease. Homology to aapQ of R. leguminosarum of 35% (sprot|AAPQ_RHILVast). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR L-AMINO ACIDS. AFFECTS THE UPTAKE AS WELL AS EFFLUX OF THESE AMINO ACIDS. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein -dependent transport system 1 HTH no signal peptide probable 4 TMHs; Family membership.
 
 
 0.909
aapM
Putative amino-acid ABC transporter permease. Homology to aapM of R. leguminosarum of 38% (sprot|AAPM_RHILV) PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM YDHWXYZ FOR AN AMINO ACID; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. Pfam: binding-protein-dependent transport system signal peptide probable 8 TMHs; Family membership.
 
 0.899
glnP
Glutamate/aspartate transport system permease protein gltJ. Homology to glnP of B. subtilis of 23% (CAA93320). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR AMINO ACID; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein-dependent transport systems inner membrane component HTH-motif probable 4 TMHs no signal peptide; Family membership.
 
 0.898
glnQ1
Glutamine transport ATP-binding protein glnQ. Homology with glnQ of B. stearothermophilus of 56% (sprot|GLNQ_BACST). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR GLUTAMINE. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. InterPro: AAA ATPase superfamily (IPR003593), ABC_transporter (IPR003439), ATP/GTP_binding site motif A (P-loop) (IPR001687) Pfam: ABC transporter no signal peptide no TMHs; High confidence in function and specificity.
 
 0.896
barA
Putative sensor-regulator protein,; Specificity unclear.
    
 0.780
azo2482
Putative hybrid sensor and regulator; Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal pepti [...]
    
 0.780
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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