STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2269Conserved hypothetical band 7 family protein. Homology to pp4834 of P.putida of 67% (trembl|Q88DJ1). InterPro: Band 7 protein (IPR001107). Pfam: SPFH domain / Band 7 family. The band 7 protein is an integral membrane protein which is thought to regulate cation conductance. A variety of proteins belong to this family. These include the prohibitins, cytoplasmic anti-proliferative proteins and stomatin, an erythrocyte membrane protein. Bacterial HflC protein also belongs to this family. probable 1 TMH. probable signal peptide (overlapping with the TMH); Family membership. (287 aa)    
Predicted Functional Partners:
FtsH
Probable cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.964
azo2268
Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein.
 
  
 0.948
hflC
Conserved hypothetical protein HflC; HflC and HflK could regulate a protease.
  
     0.692
azo0764
Probable Zn dependent peptidase; Hypothetical zinc protease-like protein y4wB. TREMBL:Q8Y2E8: 43% identity; 57% similarity. InterPro: Insulinase family (Peptidase family M16) InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. Pfam:PF00675; Peptidase_M16 (Insulinase); homoserine_dh; aldehyde dehydrogenase; PF05193:Peptidase_M16_C; precor6x_red: precorrin-6x reductase TIGRFAM:folate/biopterin transporter SignalP predicted signal peptide and TMHMM predicted transmembrane helix; Specificity unclear.
  
 0.643
azo0765
Probable Zn dependent peptidase; TREMBL:Q8Y2E9: 55% identity, 68% similarity. Hypothetical zinc protease y4wA. InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. cofactor:binds 1 zinc ion per subunit (by similarity). belongs to peptidase family m16. similarity:to y4wb. Pfam:PF00675; Peptidase_M16; 1. PF05193:Peptidase_M16_C TIGRFAM: uxuA SignalP predicted signal peptide and TMHMM predicted transmembrane helices menD: 2-succinyl-6-hydroxy-24-cyclohex; Specificity unclear.
  
 0.625
metH
Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  0.558
algH
Transcriptional regulator,; Specificity unclear; Belongs to the UPF0301 (AlgH) family.
  
    0.532
azo2312
Conserved hypothetical membrane protein. Homology to Avin02002177 of Azotobacter vinelandii of 61% (gi|53611929|ref|ZP_00090985.2|(NBCI ENTREZ)). InterPro: ABC transporter (IPR003439). Pfam: ABC transporter. no signal peptide. 5 TMHs; Conserved hypothetical protein.
    
  0.518
gstB
Probable Glutathione transferase. Homology to gstB of P. mirablilis of 29% (sprot|GT_PROMI). Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. InterPro: Glutathione S-transferase N terminus(IPR004045), Glutathione S-transferase C terminus (IPR004046) Pfam: Glutathione S-transferase, N-terminale domaine no signal peptide no TMHs; Family membership.
 
 
   0.499
azo2638
Conserved hypothetical ATPase. Homology to rsc1961 of R. solanacearum of 37% (trembl|Q8XY02). Pfam: Atpase familly associated with various cellular activities (domaine 1 from 300 aa to 499 aa, domaine 2 from 543 to 723 aa). no signal peptide. no TMHs; Conserved hypothetical protein.
   
 0.495
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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