node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
N177_0187 | N177_3469 | N177_0187 | N177_3469 | C-terminal domain of CinA type S; Protein Implicated in DNA repair function with RecA and MutS; Belongs to the CinA family. | Putative phosphatase. | 0.625 |
N177_0187 | pncB | N177_0187 | N177_1245 | C-terminal domain of CinA type S; Protein Implicated in DNA repair function with RecA and MutS; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.618 |
N177_0187 | surE | N177_0187 | N177_3617 | C-terminal domain of CinA type S; Protein Implicated in DNA repair function with RecA and MutS; Belongs to the CinA family. | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.719 |
N177_1280 | N177_3469 | N177_1280 | N177_3469 | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative phosphatase. | 0.555 |
N177_1280 | guaA | N177_1280 | N177_3489 | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.925 |
N177_1280 | guaB | N177_1280 | N177_3485 | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.843 |
N177_1280 | purA | N177_1280 | N177_0369 | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.786 |
N177_1280 | surE | N177_1280 | N177_3617 | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.705 |
N177_1433 | N177_3469 | N177_1433 | N177_3469 | Glycerophosphoryl diester phosphodiesterase. | Putative phosphatase. | 0.627 |
N177_2318 | N177_2792 | N177_2318 | N177_2792 | Phosphonate ABC transporter phosphate-binding periplasmic component; TCDB 3.A.1.9.1. | Protein RcsF. | 0.636 |
N177_2318 | N177_3469 | N177_2318 | N177_3469 | Phosphonate ABC transporter phosphate-binding periplasmic component; TCDB 3.A.1.9.1. | Putative phosphatase. | 0.679 |
N177_2792 | N177_2318 | N177_2792 | N177_2318 | Protein RcsF. | Phosphonate ABC transporter phosphate-binding periplasmic component; TCDB 3.A.1.9.1. | 0.636 |
N177_2792 | N177_3469 | N177_2792 | N177_3469 | Protein RcsF. | Putative phosphatase. | 0.548 |
N177_2792 | guaA | N177_2792 | N177_3489 | Protein RcsF. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.880 |
N177_2792 | guaB | N177_2792 | N177_3485 | Protein RcsF. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.843 |
N177_2792 | purA | N177_2792 | N177_0369 | Protein RcsF. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.710 |
N177_2792 | surE | N177_2792 | N177_3617 | Protein RcsF. | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.539 |
N177_3469 | N177_0187 | N177_3469 | N177_0187 | Putative phosphatase. | C-terminal domain of CinA type S; Protein Implicated in DNA repair function with RecA and MutS; Belongs to the CinA family. | 0.625 |
N177_3469 | N177_1280 | N177_3469 | N177_1280 | Putative phosphatase. | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.555 |
N177_3469 | N177_1433 | N177_3469 | N177_1433 | Putative phosphatase. | Glycerophosphoryl diester phosphodiesterase. | 0.627 |