STRINGSTRING
manA protein (Yersinia pseudotuberculosis) - STRING interaction network
manA: mannose-6-phosphate isomerase, class I in Yersinia pseudotuberculosis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manAmanA- mannose-6-phosphate isomerase, class I; Belongs to the mannose-6-phosphate isomerase type 1 family (359 aa)    
Predicted Functional Partners:
pgi
annotation not available (548 aa)
 
 
  0.956
manX
annotation not available (324 aa)
   
 
  0.948
manB2
annotation not available (462 aa)
 
  0.942
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (266 aa)
   
   
  0.939
pfkA
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (327 aa)
 
  0.933
glmS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (609 aa)
     
 
  0.924
mak
annotation not available (304 aa)
       
  0.913
manY
EII-Sor- PTS system, mannose/fructose/sorbose , IIC component family protein (265 aa)
   
 
    0.910
manZ_1
EIID-AGA- PTS system, mannose/fructose/sorbose , IID component family protein (292 aa)
       
    0.908
mtlD
annotation not available (387 aa)
       
  0.905
Your Current Organism:
Yersinia pseudotuberculosis
NCBI taxonomy Id: 633
Other names: ATCC 29833, Bacillus pseudotuberkulosis, Bacterium pseudotuberculosis, CCUG 5855, CIP 55.85, DSM 8992, NCTC 10275, Pasteurella pseudotuberculosis, Shigella pseudotuberculosis, Y. pseudotuberculosis, Yersinia pseudotuberculosis
Server load: low (11%) [HD]