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apt protein (Yersinia pseudotuberculosis) - STRING interaction network
"apt" - Adenine phosphoribosyltransferase in Yersinia pseudotuberculosis
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (187 aa)    
Predicted Functional Partners:
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (525 aa)
   
  0.987
purB
purB- adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (456 aa)
   
  0.966
purH
Bifunctional purine biosynthesis protein PurH; purH- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (529 aa)
   
 
  0.934
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family (214 aa)
   
 
  0.932
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (207 aa)
   
 
  0.929
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (347 aa)
   
 
  0.928
deoD
deoD- purine nucleoside phosphorylase (239 aa)
       
  0.923
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily (152 aa)
   
  0.921
ppnP
Pyrimidine/purine nucleoside phosphorylase; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions (95 aa)
         
  0.921
gsk
annotation not available (434 aa)
     
  0.917
Your Current Organism:
Yersinia pseudotuberculosis
NCBI taxonomy Id: 633
Other names: ATCC 29833, Bacillus pseudotuberkulosis, Bacterium pseudotuberculosis, CCUG 5855, CIP 55.85, DSM 8992, NCTC 10275, Pasteurella pseudotuberculosis, Shigella pseudotuberculosis, Y. pseudotuberculosis, Yersinia pseudotuberculosis
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