STRINGSTRING
tig protein (Yersinia pseudotuberculosis) - STRING interaction network
"tig" - Trigger factor in Yersinia pseudotuberculosis
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily (434 aa)    
Predicted Functional Partners:
rplW
50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (100 aa)
   
 
  0.942
rpmC
L29- ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family (63 aa)
 
 
  0.939
ppiD
annotation not available (628 aa)
 
 
  0.933
tsf
Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (285 aa)
 
 
  0.902
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20 (103 aa)
 
   
  0.858
rplX
50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (104 aa)
   
 
  0.853
rplA
50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (234 aa)
   
 
  0.843
rpsB
rpsB_bact- ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family (241 aa)
 
 
  0.825
trmD
tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs; Belongs to the RNA methyltransferase TrmD family (246 aa)
 
   
  0.823
rplD
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel (201 aa)
 
      0.823
Your Current Organism:
Yersinia pseudotuberculosis
NCBI taxonomy Id: 633
Other names: ATCC 29833, Bacillus pseudotuberkulosis, Bacterium pseudotuberculosis, CCUG 5855, CIP 55.85, DSM 8992, NCTC 10275, Pasteurella pseudotuberculosis, Shigella pseudotuberculosis, Y. pseudotuberculosis, Yersinia pseudotuberculosis
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