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lapB protein (Yersinia pseudotuberculosis) - STRING interaction network
"lapB" - Lipopolysaccharide assembly protein B in Yersinia pseudotuberculosis
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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lapBLipopolysaccharide assembly protein B; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane (389 aa)    
Predicted Functional Partners:
yciS
Lipopolysaccharide assembly protein A; Involved in the assembly of lipopolysaccharide (LPS) (103 aa)
 
   
  0.969
pgpB
annotation not available (253 aa)
 
          0.609
cutC
Copper homeostasis protein CutC; Participates in the control of copper homeostasis (254 aa)
           
  0.603
lpxH
UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (240 aa)
   
 
 
  0.599
hemX
annotation not available (374 aa)
   
          0.543
sspA
Glutathione S-transferase, N-terminal domain protein; Belongs to the GST superfamily (213 aa)
   
          0.531
lpxC
UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family (306 aa)
   
     
  0.506
ompA
annotation not available (353 aa)
         
  0.502
mreD
Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (162 aa)
   
          0.502
ftsB
Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (106 aa)
   
          0.502
Your Current Organism:
Yersinia pseudotuberculosis
NCBI taxonomy Id: 633
Other names: ATCC 29833, Bacillus pseudotuberkulosis, Bacterium pseudotuberculosis, CCUG 5855, CIP 55.85, DSM 8992, NCTC 10275, Pasteurella pseudotuberculosis, Shigella pseudotuberculosis, Y. pseudotuberculosis, Yersinia pseudotuberculosis
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