STRINGSTRING
nadC protein (Yersinia pseudotuberculosis) - STRING interaction network
"nadC" - Quinolinate phosphoribosyltransferase in Yersinia pseudotuberculosis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadCQuinolinate phosphoribosyltransferase; nadC- nicotinate-nucleotide diphosphorylase; Belongs to the NadC/ModD family (302 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily (353 aa)
 
 
  0.991
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate (533 aa)
   
  0.988
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP (401 aa)
   
  0.956
nadD
Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (220 aa)
       
  0.954
nadR
annotation not available (423 aa)
         
  0.914
mazG
annotation not available (280 aa)
       
    0.908
nudC
annotation not available (260 aa)
     
 
    0.902
ygaD
annotation not available (162 aa)
     
 
  0.902
surE
5’/3’-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5’- monophosphates and ribonucleoside 3’-monophosphates with highest affinity to 3’-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain- length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3’-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs (254 aa)
     
 
    0.901
yjjG
Nucleotidase; HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein (224 aa)
         
    0.900
Your Current Organism:
Yersinia pseudotuberculosis
NCBI taxonomy Id: 633
Other names: ATCC 29833, Bacillus pseudotuberkulosis, Bacterium pseudotuberculosis, CCUG 5855, CIP 55.85, DSM 8992, NCTC 10275, Pasteurella pseudotuberculosis, Shigella pseudotuberculosis, Y. pseudotuberculosis, Yersinia pseudotuberculosis
Server load: low (11%) [HD]