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lsrG protein (Yersinia pseudotuberculosis) - STRING interaction network
"lsrG" - (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase in Yersinia pseudotuberculosis
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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lsrG(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family (96 aa)    
Predicted Functional Partners:
lsrF
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family (291 aa)
 
 
  0.996
lsrB
annotation not available (339 aa)
 
   
  0.991
lsrK
Autoinducer-2 kinase; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3- dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (530 aa)
 
   
  0.965
lsrD_1
annotation not available (333 aa)
 
   
  0.931
lsrR
annotation not available (331 aa)
 
   
  0.923
lsrC
annotation not available (351 aa)
 
   
  0.893
mglA9
ccmA- heme ABC exporter, ATP-binding protein CcmA (527 aa)
 
   
  0.863
lsrB_1
annotation not available (331 aa)
   
   
  0.650
rbsB13
annotation not available (329 aa)
   
   
  0.650
lsrB_3
annotation not available (334 aa)
   
   
  0.650
Your Current Organism:
Yersinia pseudotuberculosis
NCBI taxonomy Id: 633
Other names: ATCC 29833, Bacillus pseudotuberkulosis, Bacterium pseudotuberculosis, CCUG 5855, CIP 55.85, DSM 8992, NCTC 10275, Pasteurella pseudotuberculosis, Shigella pseudotuberculosis, Y. pseudotuberculosis, Yersinia pseudotuberculosis
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