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ilvC protein (Yersinia pseudotuberculosis) - STRING interaction network
"ilvC" - Ketol-acid reductoisomerase in Yersinia pseudotuberculosis
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ilvCKetol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate; Belongs to the ketol-acid reductoisomerase family (492 aa)    
Predicted Functional Partners:
ilvD
ilvD- dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family (616 aa)
 
  0.995
ilvH
Acolac_sm- acetolactate synthase, small subunit (164 aa)
 
  0.985
ilvI
Acolac_lg- acetolactate synthase, large subunit, biosynthetic type (575 aa)
 
 
  0.979
ilvG
Acolac_lg- acetolactate synthase, large subunit, biosynthetic type (548 aa)
 
 
  0.977
ilvB_1
Acolac_lg- acetolactate synthase, large subunit, biosynthetic type (555 aa)
 
 
  0.974
DJ40_89
annotation not available (115 aa)
   
  0.967
ilvM
annotation not available (85 aa)
 
   
  0.945
edd
Edd- phosphogluconate dehydratase; Belongs to the IlvD/Edd family (638 aa)
 
 
  0.877
cynR_1
annotation not available (293 aa)
 
     
  0.843
thrA
annotation not available (819 aa)
 
   
  0.813
Your Current Organism:
Yersinia pseudotuberculosis
NCBI taxonomy Id: 633
Other names: ATCC 29833, Bacillus pseudotuberkulosis, Bacterium pseudotuberculosis, CCUG 5855, CIP 55.85, DSM 8992, NCTC 10275, Pasteurella pseudotuberculosis, Shigella pseudotuberculosis, Y. pseudotuberculosis, Yersinia pseudotuberculosis
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