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hslO protein (Yersinia pseudotuberculosis) - STRING interaction network
"hslO" - 33 kDa chaperonin in Yersinia pseudotuberculosis
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hslO33 kDa chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (293 aa)    
Predicted Functional Partners:
hslR
annotation not available (135 aa)
   
   
  0.924
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (379 aa)
     
   
  0.724
hslV
ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (174 aa)
   
   
  0.719
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity (622 aa)
   
   
  0.716
hslU
ATP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (443 aa)
     
   
  0.707
DJ40_2636
GMP/IMP nucleotidase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein (226 aa)
 
        0.660
uspA
annotation not available (148 aa)
           
  0.626
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA; Belongs to the phosphoenolpyruvate carboxykinase (ATP) family (539 aa)
   
        0.621
sodA
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (207 aa)
         
  0.606
htpX
annotation not available (293 aa)
           
  0.597
Your Current Organism:
Yersinia pseudotuberculosis
NCBI taxonomy Id: 633
Other names: ATCC 29833, Bacillus pseudotuberkulosis, Bacterium pseudotuberculosis, CCUG 5855, CIP 55.85, DSM 8992, NCTC 10275, Pasteurella pseudotuberculosis, Shigella pseudotuberculosis, Y. pseudotuberculosis, Yersinia pseudotuberculosis
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