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aceA protein (Yersinia pseudotuberculosis) - STRING interaction network
"aceA" - Isocit_lyase: isocitrate lyase in Yersinia pseudotuberculosis
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
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Experiments
Databases
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[Homology]
Score
aceAIsocit_lyase- isocitrate lyase (435 aa)    
Predicted Functional Partners:
aceB
malate_syn_A- malate synthase A (532 aa)
  0.999
acnB
acnB- aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family (865 aa)
     
 
  0.946
aceK
Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (575 aa)
 
   
  0.940
acnA
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (890 aa)
     
 
  0.932
eda
annotation not available (213 aa)
         
  0.925
ghrB
Glyoxylate/hydroxypyruvate reductase B; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively (326 aa)
         
  0.912
ghrB_1
annotation not available (316 aa)
         
  0.824
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family (878 aa)
           
  0.772
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA; Belongs to the phosphoenolpyruvate carboxykinase (ATP) family (539 aa)
         
  0.695
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (363 aa)
           
  0.651
Your Current Organism:
Yersinia pseudotuberculosis
NCBI taxonomy Id: 633
Other names: ATCC 29833, Bacillus pseudotuberkulosis, Bacterium pseudotuberculosis, CCUG 5855, CIP 55.85, DSM 8992, NCTC 10275, Pasteurella pseudotuberculosis, Shigella pseudotuberculosis, Y. pseudotuberculosis, Yersinia pseudotuberculosis
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