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purR protein (Yersinia pseudotuberculosis) - STRING interaction network
"purR" - HTH-type transcriptional repressor PurR in Yersinia pseudotuberculosis
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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purRHTH-type transcriptional repressor PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression (341 aa)    
Predicted Functional Partners:
rbsD
D-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (139 aa)
 
   
  0.647
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (432 aa)
       
 
  0.639
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway (308 aa)
   
  0.609
icaB
annotation not available (427 aa)
           
  0.592
rbsK5
annotation not available (309 aa)
   
  0.589
DJ40_1822
PTS_I_fam- phosphoenolpyruvate-protein phosphotransferase (858 aa)
     
 
  0.539
purE
N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (174 aa)
     
 
  0.537
glpR
annotation not available (252 aa)
   
 
      0.527
rbsB
annotation not available (305 aa)
 
 
  0.510
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA; Belongs to the phosphoenolpyruvate carboxykinase (ATP) family (539 aa)
     
   
  0.481
Your Current Organism:
Yersinia pseudotuberculosis
NCBI taxonomy Id: 633
Other names: ATCC 29833, Bacillus pseudotuberkulosis, Bacterium pseudotuberculosis, CCUG 5855, CIP 55.85, DSM 8992, NCTC 10275, Pasteurella pseudotuberculosis, Shigella pseudotuberculosis, Y. pseudotuberculosis, Yersinia pseudotuberculosis
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