STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tagg_0455Acetylornithine transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814:IPR001917; KEGG: sfu:Sfum_2649 aminotransferase class-III; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: B8D340 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)    
Predicted Functional Partners:
Tagg_0191
COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterPro IPR000310:IPR001597:IPR000192:IPR002129; KEGG: swd:Swoo_2007 pyridoxal-dependent decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; Orn/Lys/Arg decarboxylase major region; SPTR: B8D379 Pyridoxal-dependent decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain.
  
 0.951
Tagg_0004
COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: dat:HRM2_38760 GabT; PFAM: aminotransferase class-III; SPTR: B8D6H5 Pyridoxal phosphate-dependent aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.911
Tagg_0656
Pantothenate synthetase; COGs: COG1701 conserved hypothetical protein; InterPro IPR002855; PFAM: Protein of unknown function DUF137; SPTR: B8D3I1 Putative uncharacterized protein; PFAM: Protein of unknown function DUF137.
     
  0.900
Tagg_0454
InterPro IPR000620; KEGG: sfu:Sfum_3638 protein of unknown function DUF6, transmembrane; PFAM: protein of unknown function DUF6 transmembrane; SPTR: B8D3Z6 Putative uncharacterized protein; PFAM: EamA-like transporter family.
  
  
 0.672
Tagg_1262
Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR008670:IPR015590; KEGG: geo:Geob_3547 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; acyl-CoA reductase; SPTR: B8D6N9 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase family.
 
 
 0.672
Tagg_0453
Arginine--tRNA ligase; COGs: COG0018 Arginyl-tRNA synthetase; InterPro IPR015945:IPR008909; KEGG: DALR anticodon binding domain containing protein; PFAM: DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: B8D3Z5 Arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.628
Tagg_1145
COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: gbm:Gbem_0736 aminotransferase class V; PFAM: aminotransferase class V; SPTR: B8D563 Aspartate/serine transaminase; PFAM: Aminotransferase class-V.
  
 
 0.612
Tagg_0319
COGs: COG0388 amidohydrolase; InterPro IPR003010:IPR001110; KEGG: dda:Dd703_0387 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: B8D4L6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Carbon-nitrogen hydrolase.
 
  
 0.574
Tagg_0452
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983; KEGG: dol:Dole_2101 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: B8D3Z4 Aldehyde ferredoxin oxidoreductase-like protein; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
 
     0.555
Tagg_0617
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: scl:sce0669 sarcosine oxidase, beta subunit; PFAM: FAD dependent oxidoreductase; SPTR: B8D2Y9 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase.
  
  
 0.553
Your Current Organism:
Thermosphaera aggregans
NCBI taxonomy Id: 633148
Other names: T. aggregans DSM 11486, Thermosphaera aggregans DSM 11486, Thermosphaera aggregans M11TL, Thermosphaera aggregans str. DSM 11486, Thermosphaera aggregans strain DSM 11486
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