STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK99835.1DNA ligase D; KEGG: msl:Msil_1736 ATP-dependent DNA ligase; TIGRFAM: DNA ligase D; DNA polymerase LigD, polymerase domain protein; DNA polymerase LigD, ligase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. (859 aa)    
Predicted Functional Partners:
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.949
ADK99317.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.937
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.910
ADL00137.1
PFAM: protein of unknown function DUF72; KEGG: hypothetical protein.
 
    0.728
ADL01652.1
KEGG: ccs:CCNA_03759 mRNA 3'-end processing factor.
 
 0.721
ADL02044.1
KEGG: DNA topoisomerase; PFAM: DNA topoisomerase I catalytic core domain protein.
 
 
 
 0.676
ADL02259.1
KEGG: swi:Swit_1120 nucleotidyltransferase/DNA polymerase involved in DNA repair-like protein.
  
 
 0.634
ADK99644.1
TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: pzu:PHZ_c3346 histidinol-phosphate phosphatase.
   
 0.620
ADL01304.1
KEGG: ccs:CCNA_01899 DNA polymerase III, delta' subunit; TIGRFAM: DNA polymerase III, delta prime subunit; PFAM: AAA ATPase central domain protein.
   
 0.610
ADL00237.1
KEGG: bph:Bphy_5537 exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase.
 
 
 0.597
Your Current Organism:
Brevundimonas subvibrioides
NCBI taxonomy Id: 633149
Other names: B. subvibrioides ATCC 15264, Brevundimonas subvibrioides ATCC 15264, Brevundimonas subvibrioides CB81, Brevundimonas subvibrioides DSM 4735, Brevundimonas subvibrioides LMG 14903, Brevundimonas subvibrioides str. ATCC 15264, Brevundimonas subvibrioides strain ATCC 15264
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