STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
imp-2Intramembrane protease 2. (462 aa)    
Predicted Functional Partners:
cup-2
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
   
 
 0.587
SSR3
Translocon-associated protein subunit gamma.
   
 
 0.524
HSP90B1
Endoplasmin.
   
  
 0.501
Sec61a2
Protein transport protein Sec61 subunit alpha isoform 2.
   
  
 0.489
MBTPS2
Membrane-bound transcription factor site-2 protease.
      
 0.408
Your Current Organism:
Trichinella spiralis
NCBI taxonomy Id: 6334
Other names: T. spiralis
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.