STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARB_00147Calnexin homolog ARB_00147; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. (563 aa)    
Predicted Functional Partners:
ARB_02626
Protein disulfide-isomerase; Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer; Belongs to the protein disulfide isomerase family.
   
 0.966
ARB_05266
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.925
ARB_06395
Tr-type G domain-containing protein.
 
    
 0.903
ARB_07582
Uncharacterized protein.
    
 
 0.879
ARB_06843
Sugar hydrolase, putative; Belongs to the glycosyl hydrolase 31 family.
    
 0.878
ARB_05819
Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.
   
 0.819
ARB_04834
WD_REPEATS_REGION domain-containing protein.
   
 
 0.808
ARB_06436
J domain-containing protein.
   
 0.787
ARB_04533
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 
 0.693
ARB_03420
Uncharacterized protein.
   
 
 0.683
Your Current Organism:
Trichophyton benhamiae
NCBI taxonomy Id: 663331
Other names: Arthroderma benhamiae CBS 112371, T. benhamiae CBS 112371, Trichophyton benhamiae CBS 112371
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.