node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HAH_4427 | dnaN1 | HAH_4427 | HAH_0128 | PHP domain protein. | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.501 |
HAH_4427 | dnaN2 | HAH_4427 | HAH_4097 | PHP domain protein. | DNA polymerase sliding clamp. | 0.501 |
HAH_4427 | dnaN3 | HAH_4427 | HAH_4158 | PHP domain protein. | DNA polymerase sliding clamp. | 0.501 |
HAH_4427 | fen | HAH_4427 | HAH_0793 | PHP domain protein. | Flap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.768 |
HAH_4427 | lig2 | HAH_4427 | HAH_1173 | PHP domain protein. | DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.822 |
HAH_4427 | polA1 | HAH_4427 | HAH_0004 | PHP domain protein. | DNA polymerase II small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.482 |
HAH_4427 | polB1 | HAH_4427 | HAH_2356 | PHP domain protein. | DNA polymerase elongation subunit (family B). | 0.557 |
dnaN1 | HAH_4427 | HAH_0128 | HAH_4427 | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | PHP domain protein. | 0.501 |
dnaN1 | dnaN2 | HAH_0128 | HAH_4097 | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | DNA polymerase sliding clamp. | 0.911 |
dnaN1 | dnaN3 | HAH_0128 | HAH_4158 | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | DNA polymerase sliding clamp. | 0.911 |
dnaN1 | fen | HAH_0128 | HAH_0793 | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | Flap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.958 |
dnaN1 | lig2 | HAH_0128 | HAH_1173 | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.885 |
dnaN1 | pol4 | HAH_0128 | HAH_1323 | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | DNA polymerase IV. | 0.501 |
dnaN1 | polA1 | HAH_0128 | HAH_0004 | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | DNA polymerase II small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.955 |
dnaN1 | polB1 | HAH_0128 | HAH_2356 | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | DNA polymerase elongation subunit (family B). | 0.956 |
dnaN1 | rfcB | HAH_0128 | HAH_2278 | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.923 |
dnaN2 | HAH_4427 | HAH_4097 | HAH_4427 | DNA polymerase sliding clamp. | PHP domain protein. | 0.501 |
dnaN2 | dnaN1 | HAH_4097 | HAH_0128 | DNA polymerase sliding clamp. | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.911 |
dnaN2 | dnaN3 | HAH_4097 | HAH_4158 | DNA polymerase sliding clamp. | DNA polymerase sliding clamp. | 0.900 |
dnaN2 | fen | HAH_4097 | HAH_0793 | DNA polymerase sliding clamp. | Flap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.905 |