STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase isozyme I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; silverDB:661Eb00387; Belongs to the GPI family.
  
 0.975
fba
Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
 
 0.959
fruK
1-phosphofructokinase; silverDB:661Eb03972; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.933
pfkA-2
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
  
  
 
0.923
fbp
Fructose-1,6-bisphosphatase; silverDB:661Eb00636.
    
 0.919
mtlD
Mannitol-1-phosphate dehydrogenase; silverDB:661Eb05936.
 
  
 0.919
glpX
Putative glycerol metabolic protein; silverDB:661Eb00182.
   
 
 0.916
EbC_29670
Fructose-biphosphate aldolase class I, fragment; silverDB:661Eb03923.
    
 0.915
tktA
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.914
tktA-2
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.914
Your Current Organism:
Erwinia billingiae
NCBI taxonomy Id: 634500
Other names: E. billingiae Eb661, Erwinia billingiae Eb661, Erwinia billingiae str. Eb661, Erwinia billingiae strain Eb661
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.