STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
thiE1Thiamine-phosphate pyrophosphorylase ThiE1; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). (201 aa)    
Predicted Functional Partners:
thiD1
Phosphomethylpyrimidine kinase ThiD1.
 
 0.999
thiG
Thiazole synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.997
thiD2
Phosphomethylpyrimidine kinase ThiD2.
 
 0.997
thiS
Thiamin biosynthesis protein ThiS.
 
  
 0.985
thiO
Thiamine biosynthesis oxidoreductase ThiO.
 
  
 0.953
thiC
Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.943
thiE2
Thiamine-phosphate pyrophosphorylase ThiE2.
     
  0.900
moeB
Molybdopterin biosynthesis protein MoeB.
  
  
 0.654
Bgr_02510
Periplasmic phosphate binding protein.
   
    0.572
ampD
N-acetylmuramoyl-L-alanine amidase.
 
      0.504
Your Current Organism:
Bartonella grahamii
NCBI taxonomy Id: 634504
Other names: B. grahamii as4aup, Bartonella grahamii as4aup, Bartonella grahamii str. as4aup, Bartonella grahamii strain as4aup
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