| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dxs | nadE | Bgr_04670 | Bgr_07300 | 1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.538 |
| dxs | thiC | Bgr_04670 | Bgr_05720 | 1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.408 |
| dxs | thiG | Bgr_04670 | Bgr_05690 | 1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiazole synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.935 |
| moeB | thiC | Bgr_02490 | Bgr_05720 | Molybdopterin biosynthesis protein MoeB. | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.752 |
| moeB | thiD1 | Bgr_02490 | Bgr_05670 | Molybdopterin biosynthesis protein MoeB. | Phosphomethylpyrimidine kinase ThiD1. | 0.631 |
| moeB | thiD2 | Bgr_02490 | Bgr_19900 | Molybdopterin biosynthesis protein MoeB. | Phosphomethylpyrimidine kinase ThiD2. | 0.631 |
| moeB | thiE1 | Bgr_02490 | Bgr_05680 | Molybdopterin biosynthesis protein MoeB. | Thiamine-phosphate pyrophosphorylase ThiE1; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.654 |
| moeB | thiE2 | Bgr_02490 | Bgr_18340 | Molybdopterin biosynthesis protein MoeB. | Thiamine-phosphate pyrophosphorylase ThiE2. | 0.654 |
| moeB | thiG | Bgr_02490 | Bgr_05690 | Molybdopterin biosynthesis protein MoeB. | Thiazole synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.909 |
| moeB | thiS | Bgr_02490 | Bgr_05700 | Molybdopterin biosynthesis protein MoeB. | Thiamin biosynthesis protein ThiS. | 0.932 |
| nadE | dxs | Bgr_07300 | Bgr_04670 | NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.538 |
| nadE | thiC | Bgr_07300 | Bgr_05720 | NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.479 |
| nadE | thiG | Bgr_07300 | Bgr_05690 | NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Thiazole synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.533 |
| nadE | thiO | Bgr_07300 | Bgr_05710 | NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Thiamine biosynthesis oxidoreductase ThiO. | 0.435 |
| thiC | dxs | Bgr_05720 | Bgr_04670 | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.408 |
| thiC | moeB | Bgr_05720 | Bgr_02490 | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Molybdopterin biosynthesis protein MoeB. | 0.752 |
| thiC | nadE | Bgr_05720 | Bgr_07300 | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.479 |
| thiC | thiD1 | Bgr_05720 | Bgr_05670 | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Phosphomethylpyrimidine kinase ThiD1. | 0.993 |
| thiC | thiD2 | Bgr_05720 | Bgr_19900 | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Phosphomethylpyrimidine kinase ThiD2. | 0.974 |
| thiC | thiE1 | Bgr_05720 | Bgr_05680 | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Thiamine-phosphate pyrophosphorylase ThiE1; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.943 |