STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnBNitrogen regulatory protein P-II, GlnB; P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I- phosphate, the transcriptional activator of glnA. When P-II is phosphorylated, these events are reversed. In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is phosphorylated which allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme (By similarity). (112 aa)    
Predicted Functional Partners:
ACC83018.1
TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: ana:alr0990 ammonium transporter.
 
 0.990
ACC81728.1
TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: ana:alr0992 ammonium transporter.
 
 0.986
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 
 
 0.982
ACC80371.1
KEGG: ava:Ava_2898 hypothetical protein.
    
 
 0.978
ACC83774.1
KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.798
ACC79349.1
Cyclic nucleotide modulated signal transduction histidine kinase; PFAM: cyclic nucleotide-binding; ATP-binding region, ATPase domain protein; KEGG: gvi:glr2212 similar to two-component sensor histidine kinase.
  
 
 0.760
ACC83700.1
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp; KEGG: ava:Ava_0147 glutamine synthetase type I.
 
  
 0.752
ACC82261.1
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ava:Ava_1294 glutamine amidotransferase, class-II.
 
  
 0.746
ACC79740.1
PFAM: protein of unknown function DUF897; KEGG: ava:Ava_2950 protein of unknown function DUF897.
   
 
 0.691
ntcA
Transcriptional regulator NtcA, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: ava:Ava_3283 transcriptional regulator, Crp/Fnr family.
      
 0.631
Your Current Organism:
Nostoc punctiforme
NCBI taxonomy Id: 63737
Other names: N. punctiforme PCC 73102, Nostoc punctiforme ATCC 29133, Nostoc punctiforme PCC 73102, Nostoc sp. (strain ATCC 29133 / PCC 73102), Nostoc sp. ATCC 29133, Nostoc sp. PCC 73102
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