STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (327 aa)    
Predicted Functional Partners:
ACC83930.1
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; KEGG: ava:Ava_2713 citrate synthase; Belongs to the citrate synthase family.
  
 0.986
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.975
ACC79754.1
Malic enzyme, NAD-binding; PFAM: amino acid-binding ACT domain protein; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: ana:alr4596 malic enzyme.
  
 0.956
ACC81105.1
PFAM: fumarate lyase; KEGG: ava:Ava_3556 fumarate lyase.
 
  
 0.919
ACC78981.1
Aminotransferase, class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; KEGG: ava:Ava_2127 aspartate aminotransferase.
  
 0.913
ACC82510.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
  
  
 0.905
ACC81069.1
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: ana:alr3395 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.880
ACC82990.1
PFAM: aldehyde dehydrogenase; KEGG: ava:Ava_3534 aldehyde dehydrogenase.
   
 0.852
ACC82031.1
PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: ana:alr4255 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.845
ACC82876.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.838
Your Current Organism:
Nostoc punctiforme
NCBI taxonomy Id: 63737
Other names: N. punctiforme PCC 73102, Nostoc punctiforme ATCC 29133, Nostoc punctiforme PCC 73102, Nostoc sp. (strain ATCC 29133 / PCC 73102), Nostoc sp. ATCC 29133, Nostoc sp. PCC 73102
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