STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: ava:Ava_4920 glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (432 aa)    
Predicted Functional Partners:
hemA
Shikimate/quinate 5-dehydrogenase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.990
ACC82232.1
PFAM: delta-aminolevulinic acid dehydratase; KEGG: ava:Ava_3297 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.988
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
  
 0.926
ACC80523.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: ava:Ava_3474 uroporphyrin-III C-methyltransferase-like; Belongs to the precorrin methyltransferase family.
 
  
 0.792
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.611
ACC80313.1
PFAM: Uroporphyrinogen III synthase HEM4; KEGG: ana:all0287 uroporphyrinogen-III synthase.
 
  
 0.607
ACC80530.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: ana:alr0520 uroporphyrin-III C-methyltransferase.
 
   
 0.605
ACC79604.1
PFAM: protein of unknown function DUF92, transmembrane; KEGG: ava:Ava_4223 protein of unknown function DUF92, transmembrane.
 
      0.551
ACC82475.1
PFAM: ChaB family protein; KEGG: ava:Ava_4919 putative cation transport regulator ChaB.
       0.548
ACC81023.1
TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Methyltransferase type 11; Methyltransferase type 12; KEGG: ava:Ava_1613 non-ribosomal peptide synthase.
 
 
 0.521
Your Current Organism:
Nostoc punctiforme
NCBI taxonomy Id: 63737
Other names: N. punctiforme PCC 73102, Nostoc punctiforme ATCC 29133, Nostoc punctiforme PCC 73102, Nostoc sp. (strain ATCC 29133 / PCC 73102), Nostoc sp. ATCC 29133, Nostoc sp. PCC 73102
Server load: medium (76%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.