node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACC80509.1 | ACC83428.1 | Npun_R1852 | Npun_R5094 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: dvu:DVU2566 diaminopimelate decarboxylase. | PFAM: aminotransferase, class I and II; KEGG: ana:alr2765 aminotransferase. | 0.426 |
ACC80509.1 | asd | Npun_R1852 | Npun_R0848 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: dvu:DVU2566 diaminopimelate decarboxylase. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.481 |
ACC80509.1 | dapA | Npun_R1852 | Npun_R0847 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: dvu:DVU2566 diaminopimelate decarboxylase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.747 |
ACC80509.1 | dapB | Npun_R1852 | Npun_F4916 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: dvu:DVU2566 diaminopimelate decarboxylase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.534 |
ACC80509.1 | dapF | Npun_R1852 | Npun_R5229 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: dvu:DVU2566 diaminopimelate decarboxylase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.942 |
ACC80509.1 | lysA | Npun_R1852 | Npun_F5989 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: dvu:DVU2566 diaminopimelate decarboxylase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.926 |
ACC80509.1 | murE | Npun_R1852 | Npun_R2486 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: dvu:DVU2566 diaminopimelate decarboxylase. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.910 |
ACC83428.1 | ACC80509.1 | Npun_R5094 | Npun_R1852 | PFAM: aminotransferase, class I and II; KEGG: ana:alr2765 aminotransferase. | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: dvu:DVU2566 diaminopimelate decarboxylase. | 0.426 |
ACC83428.1 | dapB | Npun_R5094 | Npun_F4916 | PFAM: aminotransferase, class I and II; KEGG: ana:alr2765 aminotransferase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.925 |
ACC83428.1 | dapF | Npun_R5094 | Npun_R5229 | PFAM: aminotransferase, class I and II; KEGG: ana:alr2765 aminotransferase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.927 |
ACC83428.1 | dapL | Npun_R5094 | Npun_R3615 | PFAM: aminotransferase, class I and II; KEGG: ana:alr2765 aminotransferase. | Aminotransferase, class I and II; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.900 |
ACC83428.1 | lysA | Npun_R5094 | Npun_F5989 | PFAM: aminotransferase, class I and II; KEGG: ana:alr2765 aminotransferase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.463 |
asd | ACC80509.1 | Npun_R0848 | Npun_R1852 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: dvu:DVU2566 diaminopimelate decarboxylase. | 0.481 |
asd | dapA | Npun_R0848 | Npun_R0847 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.992 |
asd | dapB | Npun_R0848 | Npun_F4916 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.865 |
asd | dapF | Npun_R0848 | Npun_R5229 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.866 |
asd | lysA | Npun_R0848 | Npun_F5989 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.663 |
carB | dapF | Npun_R5798 | Npun_R5229 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: ava:Ava_1893 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.827 |
carB | pyrF | Npun_R5798 | Npun_R3868 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: ava:Ava_1893 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.777 |
dapA | ACC80509.1 | Npun_R0847 | Npun_R1852 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: dvu:DVU2566 diaminopimelate decarboxylase. | 0.747 |