node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SVI_3528 | SVI_3914 | SVI_3528 | SVI_3914 | Deoxycytidylate deaminase, putative. | Hydrolase, haloacid dehalogenase-like family. | 0.908 |
SVI_3528 | dut | SVI_3528 | SVI_4061 | Deoxycytidylate deaminase, putative. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.946 |
SVI_3528 | nutA | SVI_3528 | SVI_2596 | Deoxycytidylate deaminase, putative. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.901 |
SVI_3528 | tdk | SVI_3528 | SVI_1271 | Deoxycytidylate deaminase, putative. | Thymidine kinase. | 0.934 |
SVI_3528 | thyA | SVI_3528 | SVI_0925 | Deoxycytidylate deaminase, putative. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.953 |
SVI_3528 | tmk | SVI_3528 | SVI_2572 | Deoxycytidylate deaminase, putative. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.942 |
SVI_3914 | SVI_3528 | SVI_3914 | SVI_3528 | Hydrolase, haloacid dehalogenase-like family. | Deoxycytidylate deaminase, putative. | 0.908 |
SVI_3914 | cdd | SVI_3914 | SVI_2538 | Hydrolase, haloacid dehalogenase-like family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.911 |
SVI_3914 | deoA | SVI_3914 | SVI_3277 | Hydrolase, haloacid dehalogenase-like family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.902 |
SVI_3914 | deoD | SVI_3914 | SVI_3275 | Hydrolase, haloacid dehalogenase-like family. | Purine nucleoside phosphorylase. | 0.902 |
SVI_3914 | dut | SVI_3914 | SVI_4061 | Hydrolase, haloacid dehalogenase-like family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
SVI_3914 | nutA | SVI_3914 | SVI_2596 | Hydrolase, haloacid dehalogenase-like family. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.926 |
SVI_3914 | tdk | SVI_3914 | SVI_1271 | Hydrolase, haloacid dehalogenase-like family. | Thymidine kinase. | 0.916 |
SVI_3914 | thyA | SVI_3914 | SVI_0925 | Hydrolase, haloacid dehalogenase-like family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.903 |
SVI_3914 | tmk | SVI_3914 | SVI_2572 | Hydrolase, haloacid dehalogenase-like family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.902 |
SVI_3914 | udp | SVI_3914 | SVI_3884 | Hydrolase, haloacid dehalogenase-like family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.901 |
cdd | SVI_3914 | SVI_2538 | SVI_3914 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Hydrolase, haloacid dehalogenase-like family. | 0.911 |
cdd | deoA | SVI_2538 | SVI_3277 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.963 |
cdd | deoD | SVI_2538 | SVI_3275 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Purine nucleoside phosphorylase. | 0.943 |
cdd | nutA | SVI_2538 | SVI_2596 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.917 |