STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Thal_1227KEGG: sfu:Sfum_2676 1A family penicillin-binding protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase. (730 aa)    
Predicted Functional Partners:
uvrA
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.792
Thal_1226
KEGG: dal:Dalk_0740 nuclease (SNase domain protein); PFAM: nuclease (SNase domain protein); SMART: nuclease (SNase domain protein).
       0.773
Thal_0849
Peptidoglycan glycosyltransferase; KEGG: lip:LI1098 cell division protein FtsI/penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain.
  
 
 
 0.660
Thal_1079
PFAM: cell cycle protein; KEGG: lip:LI1103 cell division membrane protein; Belongs to the SEDS family.
  
   
 0.660
Thal_0483
KEGG: sat:SYN_00550 rod shape-determining protein; TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; Belongs to the SEDS family.
  
   
 0.652
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
   
 0.644
Thal_1223
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
     0.629
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
       0.567
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
  
   
 0.552
Thal_0444
Peptidase M23; KEGG: pnu:Pnuc_1297 peptidase M23B; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
 
  
 0.528
Your Current Organism:
Thermocrinis albus
NCBI taxonomy Id: 638303
Other names: T. albus DSM 14484, Thermocrinis albus DSM 14484, Thermocrinis albus HI 11/12, Thermocrinis albus str. DSM 14484, Thermocrinis albus strain DSM 14484
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