STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (377 aa)    
Predicted Functional Partners:
BAI79719.1
O-acetylhomoserine (thiol)-lyase.
 
 
 0.986
hom
Homoserine dehydrogenase.
 
 
 0.951
BAI81322.1
Methyltransferase, UbiE/COQ5 family.
  
  
 0.844
tdcB
Threonine dehydratase.
  
 
 0.834
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.827
BAI81325.1
TC 2.A.49 The Chloride Carrier/Channel (ClC) Family.
       0.827
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.817
BAI81323.1
TC 3.A.1. The ATP-binding Cassette (ABC) Superfamily.
       0.816
BAI81324.1
ABC transporter, permease; TC 3.A.1. The ATP-binding Cassette (ABC) Superfamily.
       0.816
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.801
Your Current Organism:
Deferribacter desulfuricans
NCBI taxonomy Id: 639282
Other names: D. desulfuricans SSM1, Deferribacter desulfuricans SSM1, Deferribacter desulfuricans str. SSM1, Deferribacter desulfuricans strain SSM1
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