STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Srot_1230PFAM: aminotransferase class I and II; KEGG: nfa:nfa54270 aminotransferase AlaT. (433 aa)    
Predicted Functional Partners:
ilvD
TIGRFAM: dihydroxy-acid dehydratase; KEGG: nfa:nfa42340 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.917
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.908
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
    
 0.906
Srot_1051
KEGG: msm:MSMEG_4276 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV.
  
 
 0.906
Srot_0929
PFAM: GCN5-related N-acetyltransferase; KEGG: mab:MAB_3072 N-acetylglutamate synthase.
     
 0.900
Srot_1885
PFAM: NAD-glutamate dehydrogenase; KEGG: nfa:nfa13060 putative NAD-dependent glutamate dehydrogenase.
     
 0.900
Srot_1886
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: rha:RHA1_ro06238 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 0.833
Srot_1229
PFAM: YibE/F family protein; KEGG: gbr:Gbro_1586 YibE/F family protein.
       0.824
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.822
Srot_0353
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
 0.816
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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