STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBTIGRFAM: homoserine kinase; KEGG: bpy:Bphyt_6795 homoserine kinase; PFAM: aminoglycoside phosphotransferase; Belongs to the pseudomonas-type ThrB family. (331 aa)    
Predicted Functional Partners:
ADG15455.1
KEGG: bxe:Bxe_A2381 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein.
 
  
 0.937
ADG15456.1
TIGRFAM: threonine synthase; KEGG: bpy:Bphyt_1807 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit.
    
 0.925
ADG15497.1
KEGG: bpy:Bphyt_1852 cystathionine beta-lyase; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
  
  
  0.835
ADG18564.1
KEGG: bpy:Bphyt_4287 serine O-acetyltransferase.
  
  
  0.827
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.820
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
 0.808
ADG16074.1
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: bpy:Bphyt_2770 O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
    
  0.805
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.805
ADG18833.1
O-acetylhomoserine aminocarboxypropyltransferase; KEGG: bph:Bphy_7567 hypothetical protein; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
    
  0.805
ADG14318.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.803
Your Current Organism:
Paraburkholderia sp. CCGE1002
NCBI taxonomy Id: 640511
Other names: P. sp. CCGE1002
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.