node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VNG_1295H | VNG_1296C | VNG_1295H | VNG_1296C | Hypothetical protein; Vng1295h. | Conserved hypothetical protein; Vng1296c. | 0.540 |
VNG_1295H | mat | VNG_1295H | VNG_1297C | Hypothetical protein; Vng1295h. | Conserved hypothetical protein; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. | 0.416 |
VNG_1295H | slyD | VNG_1295H | VNG_1294G | Hypothetical protein; Vng1295h. | Peptidyl-prolyl cis-trans isomerase; SlyD. | 0.594 |
VNG_1296C | VNG_1295H | VNG_1296C | VNG_1295H | Conserved hypothetical protein; Vng1296c. | Hypothetical protein; Vng1295h. | 0.540 |
VNG_1296C | gch31 | VNG_1296C | VNG_1011C | Conserved hypothetical protein; Vng1296c. | Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity (By similarity); Belongs to the archaeal-type GTP cyclohydrolase family. | 0.800 |
VNG_1296C | gch32 | VNG_1296C | VNG_1021C | Conserved hypothetical protein; Vng1296c. | Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity (By similarity); Belongs to the archaeal-type GTP cyclohydrolase family. | 0.800 |
VNG_1296C | mat | VNG_1296C | VNG_1297C | Conserved hypothetical protein; Vng1296c. | Conserved hypothetical protein; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. | 0.883 |
VNG_1296C | moaA | VNG_1296C | VNG_0085G | Conserved hypothetical protein; Vng1296c. | Molybdenum cofactor biosynthesis protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.813 |
VNG_1296C | mptA | VNG_1296C | VNG_1901C | Conserved hypothetical protein; Vng1296c. | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.800 |
VNG_1296C | ndk | VNG_1296C | VNG_1160G | Conserved hypothetical protein; Vng1296c. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.901 |
VNG_1296C | pykA | VNG_1296C | VNG_0324G | Conserved hypothetical protein; Vng1296c. | Pyruvate kinase; PykA; Belongs to the pyruvate kinase family. | 0.900 |
VNG_1296C | slyD | VNG_1296C | VNG_1294G | Conserved hypothetical protein; Vng1296c. | Peptidyl-prolyl cis-trans isomerase; SlyD. | 0.582 |
VNG_1296C | thiI | VNG_1296C | VNG_1299C | Conserved hypothetical protein; Vng1296c. | Conserved hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.568 |
gch31 | VNG_1296C | VNG_1011C | VNG_1296C | Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity (By similarity); Belongs to the archaeal-type GTP cyclohydrolase family. | Conserved hypothetical protein; Vng1296c. | 0.800 |
gch31 | gch32 | VNG_1011C | VNG_1021C | Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity (By similarity); Belongs to the archaeal-type GTP cyclohydrolase family. | Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity (By similarity); Belongs to the archaeal-type GTP cyclohydrolase family. | 0.900 |
gch31 | ndk | VNG_1011C | VNG_1160G | Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity (By similarity); Belongs to the archaeal-type GTP cyclohydrolase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.800 |
gch31 | pykA | VNG_1011C | VNG_0324G | Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity (By similarity); Belongs to the archaeal-type GTP cyclohydrolase family. | Pyruvate kinase; PykA; Belongs to the pyruvate kinase family. | 0.800 |
gch32 | VNG_1296C | VNG_1021C | VNG_1296C | Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity (By similarity); Belongs to the archaeal-type GTP cyclohydrolase family. | Conserved hypothetical protein; Vng1296c. | 0.800 |
gch32 | gch31 | VNG_1021C | VNG_1011C | Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity (By similarity); Belongs to the archaeal-type GTP cyclohydrolase family. | Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity (By similarity); Belongs to the archaeal-type GTP cyclohydrolase family. | 0.900 |
gch32 | ndk | VNG_1021C | VNG_1160G | Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity (By similarity); Belongs to the archaeal-type GTP cyclohydrolase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.800 |