STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdaDHypothetical protein; Vng1999h; Belongs to the PdaD family. (160 aa)    
Predicted Functional Partners:
speB
Agmatinase; SpeB; Belongs to the arginase family.
    
 0.924
mvaA
3-hydroxy-3-methylglutaryl-coenzyme A reductase; MvaA; Belongs to the HMG-CoA reductase family.
      
 0.828
argH
Argininosuccinate lyase; ArgH.
     
  0.800
prrIV1
ATP-dependent 26S proteinase regulatory subunit 4 homolog; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding [...]
       0.759
pyrF
Orotidine-5'-monophosphate (Ura3); PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily.
     
 0.747
aldY2
Aldehyde dehydrogenase (retinol); AldY2.
     
 0.725
nhaC3
Conserved hypothetical protein; Vng1985c.
      
 0.720
VNG_1998H
Hypothetical protein; Vng1998h.
       0.718
yjbG
Oligopeptidase; YjbG.
       0.499
leuS
leucine-tRNA synthetase; LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
   0.479
Your Current Organism:
Halobacterium salinarum
NCBI taxonomy Id: 64091
Other names: H. salinarum NRC-1, Halobacterium halobium NRC-1, Halobacterium salinarum NRC-1, Halobacterium salinarum str. NRC-1, Halobacterium salinarum strain NRC-1, Halobacterium sp. (strain NRC-1 / ATCC 700922 / JCM 11081), Halobacterium sp. (strain NRC-1), Halobacterium sp. ATCC 700922, Halobacterium sp. JCM 11081, Halobacterium sp. NRC-1
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