STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1ER00_HELROHSL_N domain-containing protein. (452 aa)    
Predicted Functional Partners:
T1EQZ9_HELRO
Abhydrolase_3 domain-containing protein.
 
      0.724
T1FQB2_HELRO
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.
  
 
 0.706
T1FMU4_HELRO
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
  
 
 0.682
T1G6I8_HELRO
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 
 0.631
T1FN77_HELRO
Uncharacterized protein; Belongs to the complex I 75 kDa subunit family.
   
 
 0.618
T1FQ84_HELRO
Uncharacterized protein.
    
 0.599
T1G2W6_HELRO
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
   
 0.584
T1FN15_HELRO
Cytochrome c domain-containing protein.
    
 0.578
T1EIZ4_HELRO
Alpha-type protein kinase domain-containing protein.
  
 
 0.568
T1EKC6_HELRO
Alpha-type protein kinase domain-containing protein.
  
 
 0.568
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.