STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGB16451.1KEGG: dsa:Desal_1093 isocitrate dehydrogenase (NADP(+)); PFAM: isocitrate/isopropylmalate dehydrogenase. (380 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
  
 0.996
EGB15838.1
KEGG: dma:DMR_39020 aconitate hydratase; TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain-containing protein.
 
 0.996
EGB14370.1
TIGRFAM: citrate synthase I; KEGG: dsa:Desal_0827 citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 
 0.966
EGB15481.1
KEGG: dsa:Desal_3826 4Fe-4S ferredoxin iron-sulfur binding domain protein.
   
 
 0.958
EGB13790.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.931
EGB13341.1
KEGG: dba:Dbac_0087 4Fe-4S ferredoxin iron-sulfur binding domain protein.
     
 0.916
EGB13344.1
PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; KEGG: dsa:Desal_1529 pyruvate ferredoxin/flavodoxin oxidoreductase.
     
 0.914
EGB13342.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dsa:Desal_1527 2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
   
 
 0.910
EGB14458.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tna:CTN_0948 2-ketoisovalerate ferredoxin reductase.
   
 
 0.910
EGB15482.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dsa:Desal_3825 2-ketoisovalerate ferredoxin reductase.
   
 
 0.910
Your Current Organism:
Desulfovibrio desulfuricans ND132
NCBI taxonomy Id: 641491
Other names: D. desulfuricans ND132, Desulfovibrio [desulfuricans] ND132, Desulfovibrio desulfuricans str. ND132, Desulfovibrio desulfuricans strain ND132, Desulfovibrio sp. ND132
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.