STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_0121Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterPro IPR006638:IPR005244:IPR013785:IPR007197; KEGG: csc:Csac_0491 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: A1HRP0 Radical SAM domain protein; PFAM: Radical SAM superfamily. (358 aa)    
Predicted Functional Partners:
Slip_1574
Small GTP-binding protein; COGs: COG1160 GTPase; InterPro IPR002917:IPR005225; KEGG: mta:Moth_1277 small GTP-binding protein domain-containing protein; PFAM: GTP-binding protein HSR1-related; SPTR: Q2RIZ8 Small GTP-binding protein domain; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.
   
 0.989
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.965
Slip_0122
KEGG: swo:Swol_1023 hypothetical protein; SPTR: Q0AY67 Uncharacterized protein.
 
  
 0.883
Slip_0120
Biotin and thiamin synthesis associated; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR013785:IPR007197:IPR010722; KEGG: dae:Dtox_0182 biotin and thiamin synthesis associated; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SPTR: C8W2Y1 Biotin and thiamin synthesis associated; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH.
 
   
0.866
Slip_0543
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352:IPR017900:IPR003149:IPR009016:IPR 001041:IPR019574:IPR001450:IPR004108:IPR017896; KEGG: swo:Swol_2436 (Fe) hydrogenase, large subunit HymC, putative; PFAM: hydrogenase large subunit domain protein; ferredoxin; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; SPTR: Q0AU79 (Fe) hydrogenase, large subunit HymC, putative; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase la [...]
 
  
 0.808
Slip_1533
Iron hydrogenase small subunit; InterPro IPR008953:IPR003149:IPR006311; KEGG: swo:Swol_1926 hypothetical protein; PFAM: iron hydrogenase small subunit; SPTR: Q0AVN1 Putative uncharacterized protein; PFAM: Iron hydrogenase small subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
 
   
 0.736
Slip_1534
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR009016:IPR017896:IPR001450:IPR004108:IPR 017900:IPR013352; KEGG: swo:Swol_1925 ferredoxin hydrogenase; PFAM: hydrogenase large subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: Ferredoxin hydrogenase; SPTR: Q0AVN2 Ferredoxin hydrogenase; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain; TIGRFAM: hydrogenases, Fe-only.
 
  
 0.695
Slip_0125
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR017896:IPR017900:IPR000283:IPR 009016:IPR003149:IPR019574:IPR001450:IPR004108:IPR013352; KEGG: swo:Swol_1017 iron hydrogenase, small subunit; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; SPTR: Q0AY73 Iron hydrogenase, small subunit; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-termi [...]
 
  
 0.652
Slip_0869
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.632
Slip_2067
Aminotransferase class-III; COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterProIPR015424:IPR016040:IPR015421:IPR005814:IPR 006151; KEGG: swo:Swol_0440 putative class-III aminotransferase; PFAM: aminotransferase class-III; Shikimate/quinate 5-dehydrogenase; SPTR: Q0AZS7 Aminotransferase; PFAM: Aminotransferase class-III.
  
  
 0.628
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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