STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_1093Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR006158:IPR007197:IPR013785; KEGG: swo:Swol_1016 magnesium-protoporphyrin IX monomethyl ester oxidative cyclase; PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Q0AY74 Magnesium-protoporphyrin IX monomethyl ester oxidative cyclase; PFAM: Radical SAM superfamily; B12 binding domain. (586 aa)    
Predicted Functional Partners:
Slip_1094
CBS domain containing protein; COGs: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; InterPro IPR000644:IPR001667:IPR004097; KEGG: swo:Swol_0602 putative manganese-dependent inorganic pyrophosphatase; PFAM: CBS domain containing protein; phosphoesterase RecJ domain protein; DHHA2 domain protein; SMART: CBS domain containing protein; SPTR: Q0AZC3 Inorganic diphosphatase; PFAM: DHH family; CBS domain; DHHA2 domain.
       0.705
Slip_0628
Conserved hypothetical protein; COGs: COG1242 Fe-S oxidoreductase; InterPro IPR006638:IPR013785:IPR007197:IPR005911; KEGG: drm:Dred_1358 putative radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: A4J489 Conserved hypothetical radical SAM protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM protein, TIGR01212 family.
    
 0.661
Slip_1091
Conserved hypothetical protein; COGs: COG3863 Uncharacterized distant relative of cell wall-associated hydrolase; KEGG: swo:Swol_0390 hypothetical protein; SPTR: Q0AZX6 Putative uncharacterized protein; PFAM: Orthopoxvirus protein of unknown function (DUF830).
       0.661
Slip_1092
KEGG: swo:Swol_0391 hypothetical protein; SPTR: Q0AZX5 Putative uncharacterized protein.
       0.661
Slip_2049
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
      0.612
Slip_2320
KEGG: pth:PTH_0750 hypothetical protein; SPTR: A5D490 Putative uncharacterized protein.
  
  
 0.602
Slip_0047
Protein of unknown function DUF327; COGs: COG1728 conserved hypothetical protein; InterPro IPR005585; KEGG: swo:Swol_0041 hypothetical protein; PFAM: protein of unknown function DUF327; SPTR: Q0B0V4 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF327).
  
     0.465
Slip_1711
Hypothetical protein; InterPro IPR010916; KEGG: pjd:Pjdr2_1344 signal transduction histidine kinase, nitrogen specific, NtrB; SPTR: C6CWF7 Sensor protein.
  
     0.415
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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