STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4R792_KOMPGRNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (547 aa)    
Predicted Functional Partners:
C4QXR4_KOMPG
Component of the holoenzyme form of RNA polymerase transcription factor TFIIH.
   
 0.999
C4QXV7_KOMPG
General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.
   
 0.999
C4QZG9_KOMPG
Transcription initiation factor TFIIH subunit 3.
   
 0.999
C4R1T2_KOMPG
5' to 3' DNA helicase, involved in nucleotide excision repair and transcription.
    
 0.999
C4R6R2_KOMPG
Component of the RNA polymerase II general transcription and DNA repair factor TFIIH.
    
 0.999
C4R8T2_KOMPG
Subunit of TFIIH and nucleotide excision repair factor 3 complexes.
    
 0.999
C4R3S2_KOMPG
TFIIE large subunit.
   
 0.997
C4R755_KOMPG
Subunit of TFIIH and nucleotide excision repair factor 3 complexes.
    
 0.997
C4R5F1_KOMPG
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
    
 0.995
C4R848_KOMPG
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
    
 0.986
Your Current Organism:
Komagataella phaffii
NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.