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tyrS protein (Methanocaldococcus sp. FS40622) - STRING interaction network
"tyrS" - Tyrosine--tRNA ligase in Methanocaldococcus sp. FS40622
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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tyrSTyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily (301 aa)    
Predicted Functional Partners:
tuf
Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (428 aa)
   
 
  0.927
trpS
Tryptophan--tRNA ligase; KEGG- mja-MJ1415 tryptophanyl-tRNA synthetase; TIGRFAM- tryptophanyl-tRNA synthetase; PFAM- aminoacyl-tRNA synthetase class Ib (367 aa)
 
   
  0.907
ADC69950.1
KEGG- mja-MJ0885 DNA polymerase B1; TIGRFAM- DNA polymerase Pol2; PFAM- DNA polymerase B exonuclease; DNA polymerase B region; SMART- DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein (2137 aa)
     
   
  0.902
ileS
Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily (1039 aa)
   
 
  0.858
eif1a
Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (102 aa)
 
   
  0.832
hisS
Histidine--tRNA ligase; KEGG- mja-MJ1000 histidyl-tRNA synthetase; TIGRFAM- histidyl-tRNA synthetase; histidyl-tRNA synthetase 2; PFAM- tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family (413 aa)
   
   
  0.831
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (650 aa)
   
 
  0.809
alaS
Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (892 aa)
   
 
  0.799
ADC70381.1
KH domain protein; KEGG- mja-MJ0443 putative RNA-processing protein; TIGRFAM- KH domain protein; PFAM- K Homology, type 1, subgroup; SMART- KH domain protein (218 aa)
 
        0.781
serS
Type-2 serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily (520 aa)
   
   
  0.779
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22, Methanocaldococcus sp. FS40622
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