node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADC69202.1 | cofC | MFS40622_0510 | MFS40622_1271 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: mja:MJ1501 hypothetical protein. | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.696 |
ADC69202.1 | cofD | MFS40622_0510 | MFS40622_0677 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: mja:MJ1501 hypothetical protein. | LPPG domain protein containing protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.752 |
ADC69202.1 | cofE | MFS40622_0510 | MFS40622_1408 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: mja:MJ1501 hypothetical protein. | F420-dependent oxidoreductase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | 0.745 |
ADC69202.1 | cofG | MFS40622_0510 | MFS40622_1713 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: mja:MJ1501 hypothetical protein. | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 0.627 |
ADC69202.1 | mer | MFS40622_0510 | MFS40622_0752 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: mja:MJ1501 hypothetical protein. | 5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. | 0.713 |
ADC69947.1 | ADC69949.1 | MFS40622_1270 | MFS40622_1272 | KEGG: mja:MJ0888 hypothetical protein. | TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; KEGG: mja:MJ0886 molybdenum cofactor biosynthesis protein (MoeA). | 0.792 |
ADC69947.1 | cofC | MFS40622_1270 | MFS40622_1271 | KEGG: mja:MJ0888 hypothetical protein. | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.807 |
ADC69949.1 | ADC69947.1 | MFS40622_1272 | MFS40622_1270 | TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; KEGG: mja:MJ0886 molybdenum cofactor biosynthesis protein (MoeA). | KEGG: mja:MJ0888 hypothetical protein. | 0.792 |
ADC69949.1 | cofC | MFS40622_1272 | MFS40622_1271 | TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; KEGG: mja:MJ0886 molybdenum cofactor biosynthesis protein (MoeA). | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.806 |
ADC69949.1 | cofD | MFS40622_1272 | MFS40622_0677 | TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; KEGG: mja:MJ0886 molybdenum cofactor biosynthesis protein (MoeA). | LPPG domain protein containing protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.553 |
ADC70287.1 | cofC | MFS40622_1616 | MFS40622_1271 | TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; KEGG: mja:MJ1001 ribosomal protein S6 modification protein 2 (RimK). | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.590 |
ADC70287.1 | cofD | MFS40622_1616 | MFS40622_0677 | TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; KEGG: mja:MJ1001 ribosomal protein S6 modification protein 2 (RimK). | LPPG domain protein containing protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.913 |
ADC70287.1 | cofE | MFS40622_1616 | MFS40622_1408 | TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; KEGG: mja:MJ1001 ribosomal protein S6 modification protein 2 (RimK). | F420-dependent oxidoreductase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | 0.902 |
ADC70461.1 | cofC | MFS40622_1791 | MFS40622_1271 | TIGRFAM: isopropylmalate/citramalate/homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mja:MJ0503 trans-homoaconitate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.580 |
ADC70461.1 | cofH | MFS40622_1791 | MFS40622_0622 | TIGRFAM: isopropylmalate/citramalate/homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mja:MJ0503 trans-homoaconitate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.596 |
cofC | ADC69202.1 | MFS40622_1271 | MFS40622_0510 | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: mja:MJ1501 hypothetical protein. | 0.696 |
cofC | ADC69947.1 | MFS40622_1271 | MFS40622_1270 | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | KEGG: mja:MJ0888 hypothetical protein. | 0.807 |
cofC | ADC69949.1 | MFS40622_1271 | MFS40622_1272 | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; KEGG: mja:MJ0886 molybdenum cofactor biosynthesis protein (MoeA). | 0.806 |
cofC | ADC70287.1 | MFS40622_1271 | MFS40622_1616 | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; KEGG: mja:MJ1001 ribosomal protein S6 modification protein 2 (RimK). | 0.590 |
cofC | ADC70461.1 | MFS40622_1271 | MFS40622_1791 | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | TIGRFAM: isopropylmalate/citramalate/homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mja:MJ0503 trans-homoaconitate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.580 |