STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL44052.1TIGRFAM: DNA polymerase LigD, polymerase domain protein; KEGG: saq:Sare_4351 DNA polymerase LigD polymerase subunit. (302 aa)    
Predicted Functional Partners:
ADL44051.1
KEGG: saq:Sare_4352 DNA polymerase LigD ligase region; TIGRFAM: DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein.
  
 0.999
ADL44706.1
KEGG: cai:Caci_5248 DNA polymerase LigD, ligase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; PFAM: ATP dependent DNA ligase.
  
 0.998
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.961
ADL45201.1
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: saq:Sare_1489 ATP-dependent DNA ligase.
   
 0.960
ADL48679.1
TIGRFAM: DNA polymerase LigD, polymerase domain protein; KEGG: saq:Sare_4039 DNA polymerase LigD polymerase subunit.
  
  
 
0.920
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
 0.703
ADL49471.1
PHP domain protein; KEGG: saq:Sare_0226 hypothetical protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein.
 
   
 0.414
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.