| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ahcY | hom | sync_0108 | sync_0941 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | 0.815 |
| ahcY | metB | sync_0108 | sync_0623 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Cystathionine beta-lyase/cystathionine gamma-synthase; Identified by match to protein family HMM PF01053. | 0.838 |
| ahcY | metH | sync_0108 | sync_1353 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.961 |
| ahcY | sync_0622 | sync_0108 | sync_0622 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Possible cystathionine gamma-synthase; Identified by match to protein family HMM PF01053. | 0.919 |
| ahcY | thrB | sync_0108 | sync_1869 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.800 |
| cysE | hom | sync_0087 | sync_0941 | Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | 0.821 |
| cysE | metB | sync_0087 | sync_0623 | Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Cystathionine beta-lyase/cystathionine gamma-synthase; Identified by match to protein family HMM PF01053. | 0.867 |
| cysE | metH | sync_0087 | sync_1353 | Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.482 |
| cysE | thrB | sync_0087 | sync_1869 | Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.836 |
| glk | thrB | sync_1868 | sync_1869 | Glucokinase; Identified by match to protein family HMM PF02685; match to protein family HMM TIGR00749; Belongs to the bacterial glucokinase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.781 |
| hom | ahcY | sync_0941 | sync_0108 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.815 |
| hom | cysE | sync_0941 | sync_0087 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | 0.821 |
| hom | ilvE | sync_0941 | sync_1354 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.884 |
| hom | metB | sync_0941 | sync_0623 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | Cystathionine beta-lyase/cystathionine gamma-synthase; Identified by match to protein family HMM PF01053. | 0.868 |
| hom | metH | sync_0941 | sync_1353 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.944 |
| hom | sync_0622 | sync_0941 | sync_0622 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | Possible cystathionine gamma-synthase; Identified by match to protein family HMM PF01053. | 0.868 |
| hom | thrB | sync_0941 | sync_1869 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.994 |
| hom | thrC | sync_0941 | sync_2943 | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.950 |
| ilvE | hom | sync_1354 | sync_0941 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | 0.884 |
| ilvE | metB | sync_1354 | sync_0623 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Cystathionine beta-lyase/cystathionine gamma-synthase; Identified by match to protein family HMM PF01053. | 0.913 |