| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aspC | hisC | sync_1671 | sync_2666 | Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155. | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141. | 0.917 |
| aspC | pheA | sync_1671 | sync_0377 | Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155. | Prephenate dehydratase; Identified by match to protein family HMM PF00800; match to protein family HMM PF01842. | 0.917 |
| aspC | tyrA | sync_1671 | sync_0447 | Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155. | Prephenate dehydrogenase; Identified by match to protein family HMM PF02153; match to protein family HMM PF02558; match to protein family HMM PF02737; match to protein family HMM PF03807. | 0.912 |
| hisA | hisB | sync_1723 | sync_0260 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007. | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. | 0.982 |
| hisA | hisC | sync_1723 | sync_2666 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007. | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141. | 0.811 |
| hisA | hisD | sync_1723 | sync_2362 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.983 |
| hisA | hisH-1 | sync_1723 | sync_0172 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.993 |
| hisA | hisH-2 | sync_1723 | sync_0969 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.994 |
| hisA | hisIE | sync_1723 | sync_1899 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007. | Histidine biosynthesis bifunctional protein HisIE; Identified by similarity to SP:O34912; match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family. | 0.999 |
| hisA | sync_0176 | sync_1723 | sync_0176 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.979 |
| hisB | hisA | sync_0260 | sync_1723 | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007. | 0.982 |
| hisB | hisC | sync_0260 | sync_2666 | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141. | 0.996 |
| hisB | hisD | sync_0260 | sync_2362 | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.997 |
| hisB | hisH-1 | sync_0260 | sync_0172 | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.993 |
| hisB | hisH-2 | sync_0260 | sync_0969 | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.993 |
| hisB | hisIE | sync_0260 | sync_1899 | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. | Histidine biosynthesis bifunctional protein HisIE; Identified by similarity to SP:O34912; match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family. | 0.999 |
| hisB | sync_0176 | sync_0260 | sync_0176 | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.991 |
| hisC | aspC | sync_2666 | sync_1671 | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141. | Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155. | 0.917 |
| hisC | hisA | sync_2666 | sync_1723 | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141. | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007. | 0.811 |
| hisC | hisB | sync_2666 | sync_0260 | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141. | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. | 0.996 |